Platelets are tiny cells circulating in the blood that bind together to aid in wound healing.
What Is the Difference Between PRP and PRF?
PRP (Platelet-Rich Plasma)
- Blood is spun at a high speed, which separates the plasma layer from the rest of the blood.
- Contains a concentration of platelets approximately 2-5 times what is found in the body.
- Anticoagulant additives are used to prevent clotting of the blood during injection.
- Growth factors are released over the course of a few hours.
- Typically administered through microneedling or as a facial.
- Most effective for uneven skin tone, acne scars, hyperpigmentation, wrinkles, or fine lines.
- Less effective for hollows and deep lines.
- The best results are seen with 3-4 treatments spaced four weeks apart.
PRF (Platelet-Rich Fibrin)
- Blood is spun at a lower speed, which preserves the fibrin, stem cells, and white blood cells within the layer of platelets.
- Contains a higher concentration of platelets, with approximately 10 times the amount that is found in the body, offering more healing potential.
- No addition of anticoagulants is required.
- Growth factors are released slowly for up to a week through signaling of the platelets by the spongy fibrin matrix.
- Typically administered as a natural injectable filler.
- Effective for addressing deeper wrinkles, hollowing, and more advanced aging symptoms, in addition to being useful for uneven skin tone, acne scars, hyperpigmentation, wrinkles, or fine lines.
- Successful at adding volume; widely known as a natural filler.
- Ideal outcome is seen with two treatments spaced six weeks apart.